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Thursday 6 March 2014

ANAEMIA BE HEREDITARY

Yes, anaemia may be genetic. Hereditary disorders shorten the life-span of the red blood cell and lead to am

(for example, sickle cell anaemia). Hereditary disorders can also cause anaemia by impairing the production of I Hemoglobin (for example, alpha thalassemia and beta lhalassemia).
Depending on the degree of the genetic abnormality, hereditary anaemias may cause mild, moderate, or severe unnnnia. In fact, some may be too severe to be compatible will) life and may result in death of the fetus (unborn infant). On I he other hand, some of these anaemias are so mild that lie not noticeable and are incidentally revealed during blood work.


What is a Complete Blood Cell (CBC) Count


A CBC is a test for counting and examining the different types of cells in the blood. Six component measurements make up a CBC test: 1. Red blood cell (RBC) count: The RBC count is done to determine if the number of red blood cells is low (anaemia) or high (polycythemia).

Haematocrit: The Haematocrit is specifically a measure of how much of the biood is made of red cells.
Haemoglobin: Haemoglobin is a red pigment that imparts the familiar red colour to red blood cells and to blood. Functionally, haemoglobin is the key chemical compound that combines with oxygen from the lungs and carries the oxygen from the lungs to cells throughout the body. Oxygen is essential for all cells in the body to
produce energy.

Low haemoglobin level: Low haemoglobin is called anaemia. When there is a low haemoglobin level, there is often a low red blood cell count and a low Haematocrit, too. Reference ranges are slightly different from one source to another, but typically haemoglobin of less than 13.5 is abnormal in men less than 12.0 in women. White blood cell (WBC) count. Differential blood count. Platelet count.
Only the first three of these tests: the red blood cell (RBC) count, the Haematocrit, and the haemoglobin, are relevant to the diagnosis of anaemia.


Additionally, Mean Corpuscular Volume (MCV) is also often reported in a CBC, which basically measures the average volume of red blood cells in a blood sample. This is important in distinguishing the causes of anaemia. Units of MCV are reported in femtoliters, a fraction of one millionth of a litre.

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